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Original Research
Online Published: 28 Aug 2014
 
RMJ. 2014; 39(3): 261-164


Complete blood count abnormalities associated with malaria and its response to treatment in children

Muhammad Asim Ikram, Muhammad Khalid, Aisha Sajid.


Abstract
Objectives: To evaluate the hematological derangements associated with malaria and response to treatment in children.
Methodology: It was a retrospective cross-sectional study using convenience sampling, carried out in the Pediatrics and Pathology departments, Madina Teaching Hospital, Faisalabad, Pakistan from November 2012 to October 2013. All children up to age 16 years, who were suffering from malaria, were included in the study.
Results: Out of 104 children, 66 (63.5%) were male and 38 (36.5%) were female. Anemia was found in 58 (55.8%) children. Clinically, Splenomegaly was present in 75 (72.1%) of patients (p=0.04). Thrombocytopenia (platelets count <150,000/µL) was found in 82 (78.8%) of children (p=0.001). Most of the patient (91.5%) responded to 4 doses of chloroquine (CQ) and only 8.5% were CQ resistant.
Conclusion: In an acute febrile illness with marked thrombocytopenia, P. vivax malaria should be kept as a differential diagnosis.

Key words: Vivax Malaria, thrombocytopenia, splenomegaly, chloroquine resistance, primaquine


 
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Pubmed Style

Ikram MA, Khalid M, Sajid A. Complete blood count abnormalities associated with malaria and its response to treatment in children. RMJ. 2014; 39(3): 261-164.

Web Style

Ikram MA, Khalid M, Sajid A. Complete blood count abnormalities associated with malaria and its response to treatment in children. https://www.rmj.org.pk/?mno=151892 [Access: March 13, 2025].

AMA (American Medical Association) Style

Ikram MA, Khalid M, Sajid A. Complete blood count abnormalities associated with malaria and its response to treatment in children. RMJ. 2014; 39(3): 261-164.


Vancouver/ICMJE Style

Ikram MA, Khalid M, Sajid A. Complete blood count abnormalities associated with malaria and its response to treatment in children. RMJ. (2014), [cited March 13, 2025]; 39(3): 261-164.


Harvard Style

Ikram, M. A., Khalid, . M. & Sajid, . A. (2014) Complete blood count abnormalities associated with malaria and its response to treatment in children. RMJ, 39 (3), 261-164.


Turabian Style

Ikram, Muhammad Asim, Muhammad Khalid, and Aisha Sajid. 2014. Complete blood count abnormalities associated with malaria and its response to treatment in children. Rawal Medical Journal, 39 (3), 261-164.


Chicago Style

Ikram, Muhammad Asim, Muhammad Khalid, and Aisha Sajid. "Complete blood count abnormalities associated with malaria and its response to treatment in children." Rawal Medical Journal 39 (2014), 261-164.


MLA (The Modern Language Association) Style

Ikram, Muhammad Asim, Muhammad Khalid, and Aisha Sajid. "Complete blood count abnormalities associated with malaria and its response to treatment in children." Rawal Medical Journal 39.3 (2014), 261-164. Print.


APA (American Psychological Association) Style

Ikram, M. A., Khalid, . M. & Sajid, . A. (2014) Complete blood count abnormalities associated with malaria and its response to treatment in children. Rawal Medical Journal, 39 (3), 261-164.


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