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2025, Vol: 50, Issue: 1
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Review Article 


Determinants and measurement of quality of life in patients with Inflammatory Bowel Disease: A Systematic Review

Lining Wang, Norafisyah Makhdzir, Zarina Haron, Hongyun Chen.


Abstract
Objective: To explore the determinants of quality of life in patients with inflammatory bowel disease and evaluate the specific measurement instruments used.
Methodology: This systematic review had Literature searches across five databases: PubMed, Scopus, Web of Science, Embase, and Google Scholar. Studies published between January 1, 2004, and January 1, 2024, that utilized validated QoL measurement tools and statistically analyzed associated factors were included.
Results: The 19 included studies summarized three main dimensions that affect quality of life: social dimension, physical dimension and psychological dimension.
Conclusion: QoL is influenced by the complex interplay of social, physiological, and psychological factors. While existing measurement tools are reliable, they vary in sensitivity, particularly in capturing individual patient experiences and specific symptoms such as fatigue. Uneven geographical distribution of studies, a lack of large-scale longitudinal research, and underrepresentation of key populations hinder a comprehensive understanding of the chronic progression and diverse needs of IBD patients. Future efforts should prioritize patient-centered strategies, including the development of more specific tools to address these gaps and implement targeted interventions to effectively enhance the QoL of IBD patients.

Key words: Quality of life, inflammatory bowel disease, psychosocial factors, instrumentation.


 
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How to Cite this Article
Pubmed Style

Wang L, Makhdzir N, Haron Z, Chen H. Determinants and measurement of quality of life in patients with Inflammatory Bowel Disease: A Systematic Review. RMJ. 2025; 50(1): 240-245. doi:10.5455/rmj.20241030082802

Web Style

Wang L, Makhdzir N, Haron Z, Chen H. Determinants and measurement of quality of life in patients with Inflammatory Bowel Disease: A Systematic Review. https://www.rmj.org.pk/?mno=226727 [Access: March 13, 2025]. doi:10.5455/rmj.20241030082802

AMA (American Medical Association) Style

Wang L, Makhdzir N, Haron Z, Chen H. Determinants and measurement of quality of life in patients with Inflammatory Bowel Disease: A Systematic Review. RMJ. 2025; 50(1): 240-245. doi:10.5455/rmj.20241030082802


Vancouver/ICMJE Style

Wang L, Makhdzir N, Haron Z, Chen H. Determinants and measurement of quality of life in patients with Inflammatory Bowel Disease: A Systematic Review. RMJ. (2025), [cited March 13, 2025]; 50(1): 240-245. doi:10.5455/rmj.20241030082802


Harvard Style

Wang, L., Makhdzir, . N., Haron, . Z. & Chen, . H. (2025) Determinants and measurement of quality of life in patients with Inflammatory Bowel Disease: A Systematic Review. RMJ, 50 (1), 240-245. doi:10.5455/rmj.20241030082802


Turabian Style

Wang, Lining, Norafisyah Makhdzir, Zarina Haron, and Hongyun Chen. 2025. Determinants and measurement of quality of life in patients with Inflammatory Bowel Disease: A Systematic Review. Rawal Medical Journal, 50 (1), 240-245. doi:10.5455/rmj.20241030082802


Chicago Style

Wang, Lining, Norafisyah Makhdzir, Zarina Haron, and Hongyun Chen. "Determinants and measurement of quality of life in patients with Inflammatory Bowel Disease: A Systematic Review." Rawal Medical Journal 50 (2025), 240-245. doi:10.5455/rmj.20241030082802


MLA (The Modern Language Association) Style

Wang, Lining, Norafisyah Makhdzir, Zarina Haron, and Hongyun Chen. "Determinants and measurement of quality of life in patients with Inflammatory Bowel Disease: A Systematic Review." Rawal Medical Journal 50.1 (2025), 240-245. Print. doi:10.5455/rmj.20241030082802


APA (American Psychological Association) Style

Wang, L., Makhdzir, . N., Haron, . Z. & Chen, . H. (2025) Determinants and measurement of quality of life in patients with Inflammatory Bowel Disease: A Systematic Review. Rawal Medical Journal, 50 (1), 240-245. doi:10.5455/rmj.20241030082802


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