Abstract
Objectives: To assess the clinical presentation, associated anomalies and outcome of patients born with congenital pyloric atresia.
Methodology: A case series study conducted at the Department of Pediatric Surgery, Chandka Medical College, Larkana, Pakistan from 2006 to 2014. All patients with Congenital Pyloric Atresia (CPA) were analyzed for above mentioned objectives.
Results: During the study period, 7 patients (4 Male and 3 Female) had CPA. Six (85.7%) babies were products of consanguous marriages. Most had low birth weight. All presented with non-bilious vomiting and epigastric distention. Epidermolysis bullosa, anorectal malformation and cardiac anomaly were noted. All patients underwent surgery. Type I CPA was the common anatomical lesion (71.42%). Heineke-Mickulicz pyloroplsty was performed in five cases while in two patients, gastroduodenostomy was used to bypass the obstruction. Five (71.4%) patients survived while 2 (28.6%) patients expired.
Conclusion: Congenital Pyloric Atresia is a rare cause of non-bilious vomiting in the newborn babies. If the associated anomalies are less severe and patient presented early and managed timely, the outcome can be better.

Key words: Gastric outlet obstruction, congenital pyloric atresia, non bilious vomiting, new born babies