ISSN 0303-5212
 
2026, Vol: 51, Issue: 2
51 / 2Current Issue Online FirstArchiveAims and ScopeAbstracting & IndexingMost Accessed ArticlesMost Downloaded ArticlesMost Cited Articles
Required files to be uploaded

Author_Certificate-old
Bank Reciept

Original Research 


Effects of antidepressent drugs on renal function and Hba1c level in male population of Khyber Pakhtunkhawa, Pakistan

M. M Yousaf, Sajjad Rehman, Masharib Syed, Gul Rukh Afridi.


Abstract
Objective: To study the effects of various antidepressant drugs on the HbA1c level and renal functions in male population of our province of Khyber Pakhtunkhawa.
Methodology: This hospital based cross sectional study was conducted to assess the effects of medium term use of (03- 36 months) anti-depressant drugs on the HbA1c level and renal functions in male population of Northern Pakistan in the province of Khyber Pakhtunkhawa. It comprised of 117 males in the age group of 18-60 years. The blood sample was analyzed for serum creatinine, urea and HbA1c.
Results: The mean serum urea of for SSRI group (25.76±7.31mg/dl) was higher than control (24.50±5.14 mg/dl) and TCA group (24.88 ±2.66 mg/dl) (p= 0.02). The mean serum creatinine of control group was 1.10 ±0.23 mg/dl, for SSRI group was 1.76±0.14 mg/dl and for TCA was 1.63±0.45 mg/dl. The mean HbA1c of control group was 5.91± 0.58, for SSRI was 5.70±0.51 and for TCA it was 5.66±0.55%. HbA1c was negatively correlated with age, BMI and duration in month for TCA. The correlation with duration in month was highly significant (p=0.34). No significant correlation was found with dosage in mg per day in both the patient group.
Conclusions: Medium term use of anti-depressant may cause obesity in male population and may impair renal function. The effect on the HbA1c level is still not clear and needs further studies.

Key words: Anti-depressant, urea, creatinnie, HbA1c.


 
ARTICLE TOOLS
Abstract
PDF Fulltext
How to cite this articleHow to cite this article
Citation Tools
Related Records
 Articles by M. M Yousaf
Articles by Sajjad Rehman
Articles by Masharib Syed
Articles by Gul Rukh Afridi
on Google
on Google Scholar

How to Cite this Article
Pubmed Style

Yousaf MM, Rehman S, Syed M, Afridi GR. Effects of antidepressent drugs on renal function and Hba1c level in male population of Khyber Pakhtunkhawa, Pakistan. RMJ. 2017; 42(1): 13-17.

Web Style

Yousaf MM, Rehman S, Syed M, Afridi GR. Effects of antidepressent drugs on renal function and Hba1c level in male population of Khyber Pakhtunkhawa, Pakistan. https://www.rmj.org.pk/?mno=240824 [Access: June 23, 2026].

AMA (American Medical Association) Style

Yousaf MM, Rehman S, Syed M, Afridi GR. Effects of antidepressent drugs on renal function and Hba1c level in male population of Khyber Pakhtunkhawa, Pakistan. RMJ. 2017; 42(1): 13-17.


Vancouver/ICMJE Style

Yousaf MM, Rehman S, Syed M, Afridi GR. Effects of antidepressent drugs on renal function and Hba1c level in male population of Khyber Pakhtunkhawa, Pakistan. RMJ. (2017), [cited June 23, 2026]; 42(1): 13-17.


Harvard Style

Yousaf, M. M., Rehman, . S., Syed, . M. & Afridi, . G. R. (2017) Effects of antidepressent drugs on renal function and Hba1c level in male population of Khyber Pakhtunkhawa, Pakistan. RMJ, 42 (1), 13-17.


Turabian Style

Yousaf, M. M, Sajjad Rehman, Masharib Syed, and Gul Rukh Afridi. 2017. Effects of antidepressent drugs on renal function and Hba1c level in male population of Khyber Pakhtunkhawa, Pakistan. Rawal Medical Journal, 42 (1), 13-17.


Chicago Style

Yousaf, M. M, Sajjad Rehman, Masharib Syed, and Gul Rukh Afridi. "Effects of antidepressent drugs on renal function and Hba1c level in male population of Khyber Pakhtunkhawa, Pakistan." Rawal Medical Journal 42 (2017), 13-17.


MLA (The Modern Language Association) Style

Yousaf, M. M, Sajjad Rehman, Masharib Syed, and Gul Rukh Afridi. "Effects of antidepressent drugs on renal function and Hba1c level in male population of Khyber Pakhtunkhawa, Pakistan." Rawal Medical Journal 42.1 (2017), 13-17. Print.


APA (American Psychological Association) Style

Yousaf, M. M., Rehman, . S., Syed, . M. & Afridi, . G. R. (2017) Effects of antidepressent drugs on renal function and Hba1c level in male population of Khyber Pakhtunkhawa, Pakistan. Rawal Medical Journal, 42 (1), 13-17.


Author LoginReviewer LoginEditorial PoliciesConflict of Interest PolicyPlagiarism PolicyAdvertising Policy

About Rawal Medical Journal

Publication, subscription and Editorial office PMA House G/220-B Liaquat Road, Rawalpindi. Phone: 051-555-9812, Fax: 051-553-7088 Email: drnkhokhar@ya ... Read more.



For best results, please use Internet Explorer or Google Chrome.

Contact Information